In individuals with a confirmed diagnosis,
the presence or level of a prognostic biomarker is used to identify the
likelihood of a clinical event, disease recurrence or progression, independent
of the effects of a specific intervention.
biomarkers may be used to refine criteria for disease diagnosis or staging. A
biomarker may be both prognostic and predictive.
CD4+ lymphocyte count in individuals with human
immunodeficiency virus, to identify those at elevated risk of progression to
Acquired Immunodeficiency Syndrome.