Available courses

Stem cells therapy and applications

Date: 14th September 2021 at 18:00 CET

Speaker: Dr.Yael Porat (IL)   Moderator: Dr. Dganit Itzhaky (IL)     Webinar manager: Dr. Svetlana Evgina (RU)

The speaker will present a unique patented technology employing activated immune dendritic cellsc that specifically direct stem/progenitor cell therapeutic activity in-vitro which results in an enriched endothelial progenitor cells (EnEPCs; BGC101) product generated from a standard blood draw within a day. She will report long-term outcomes of a " first in human "pilot study of BGC101 for treating patients with severe Critical Limb Ischemia (CLI) with no available surgical option. Stem/progenitor cell treatments with bone-marrow-derived cells show promise in treating CLI, albeit not without adverse events related to cell mobilization and collection. As of 2020, 4 years after treatment, the therapy shows promising therapeutic effects in objective outcomes including limb salvage, increased leg blood flow and wound healing, as well as in walking ability, reduction of pain, decreased usage of narcotic medications and improved quality of life.

The webinar is accessible for EFLM Academy members only.

The general principles of laboratory biosafety

Date: 23rd November 2021 at 18:00 CET

Speaker: Dr. Gijsbert van Willigen (NL)    Moderator: Dr. Dionysis Vourtsis (GR)     Webinar manager: Dr. Oguzhan Zengi (TR)

The health ...

The webinar is accessible for EFLM Academy members only.

Myths and facts about vitamin D

Date: 15th June 2021 at 18:00 CET

Speaker: Dr. Ali Unlu (TR)   Moderator: Dr. Sedat Abusoglu (TR)     Webinar manager: Dr. Oguzhan Zengi (TR)

The health effects of vitamin D were determined on bone health and calcium-phosphate metabolism. The association of vitamin D with many diseases caused a serious increase in scientific articles as well as an increase in analysis in routine laboratory practice. Vitamin D analysis, which is increasingly emphasized with both scientific and media approaches, seriously occupies routine biochemistry laboratories. The efficacy of vitamin D in various diseases is observed in the lower steps of the evidence-based medicine pyramid such as animal and laboratory studies. However, vitamin D cannot find a place for itself in cohort studies, meta-analyses, and clinical practice treatment guidelines, which are the higher steps of the pyramid. This presentation will address the myths and facts about vitamin D from the perspective of evidence-based medicine. This presentation will also examine vitamin D from a laboratory point of view, such as reference intervals, analytical techniques...

The webinar is accessible for EFLM Academy members only.

Haemostatic disorders in COVID-19 patients

Date: 20th April 2021 at 18:00 CET

Speaker: Dr. Tatiana Vavilova (RU)   Moderator: Dr. Ksenia Zagorodnikova (RU)     Webinar manager: Dr. Svetlana Evgina (RU)

The pathogenesis of COVID-19 is closely related to haemostatic disorders and the development of hypercoagulability. Clinical manifestations are determined by microthrombosis in the pulmonary circulation and other parts of the vascular bed. However, coagulopathy in COVID-19 is different from DIC or sepsis and is being actively studied. Already from the first months of pandemic, it became clear that one of the key methods of treatment for severe infection should be antithrombotic therapy. The presentation will address the mechanisms of haemostasisc disorders in COVID-19, laboratory diagnostic methods, principles of anticoagulation and it’s monitoring. International recommendations for the diagnosis and correction of haemostatic disorders in COVID-19 will be considered.

The webinar is accessible for EFLM Academy members only.

Reference intervals verification by indirect methods

Date: 2nd March 2021 at 18:00 CET

Speaker: Dr. Matteo Vidali (IT)   Moderator: Dr. Andrea Padoan (IT)     Webinar manager: Dr. Dganit Itzhaky (IL)

Indirect methods are data mining techniques for establishing reference intervals. Despite limitations (no precise control of the reference population and preanalytical factors, no consensus on the best procedure to select data or the best statistical algorithm), they present many advantages over the traditional direct approach: reduced costs, better matching between preanalytical and analytical conditions with routine conditions, narrower confidence limits, usefulness in specific age groups or with uncommon sample types, possibility to derive continuous reference limits.

In this presentation, advantages, limitations and the main statistical algorithms of the indirect approach will be introduced. The use of indirect methods for reference intervals verification will be discussed.

The webinar is accessible for EFLM Academy members only.

Verification of quantitative methods

Date: 26th January 2021 at 18:00 CET

Speaker: Dr. Dora Vuljanic (HR)   Moderator: Dr. Vanja Radišic Biljak (HR)     Webinar manager: Dr. Darko Cerne (SLO)

Method comparison is an important step of every verification and validation procedure in a laboratory setting. In this presentation, the basic concepts of a method comparison study will be addressed. The main focus will be on the experimental protocol for comparison of quantitative methods, including remarks on statistical methods and results interpretation, and present an example of a method comparison experiment.

The webinar is accessible for EFLM Academy members only.

The present and future of POCT

Date: 29th September 2020 at 18:00 CET

Speaker: Kleanthi Dima (GR)   Moderator: Petros Karkalousos (GR)     Webinar manager: Petros Karkalousos (GR)

Dr Kleanthi Dima will provide an overview– from the European perspective – of the opportunities that POCT can provide while identifying the limitations to be considered when choosing whether to implement POCT or not, the  clinically relevant analytical techniques, the current technologies, clinical applications, networking and quality issues, and regulatory aspects. In addition, latest technologies, e.g., novel POCT applications of molecular testing for the rapid identification of infectious agents as well as for non-pathogen-related problems will be presented. Another new area of POCT includes the companion diagnostics which help with the appropriate treatment choice, the continuous measurement of metabolites such as continuous transdermal glucose testing, and the Wearables. Finally, a short review of POCT for COVIT 19 will close the presentation.


Date: 30th June 2020 at 18:00 CET

Speaker: Dr. José A. T. Poloni (BR)   Moderator: Dr. Timo Kouri (FIN)     Webinar manager: Dr. Darko Cerne (SLO)

Urinalysis is one of the most common tests performed in Clinical Analysis laboratories worldwide. Despite the simplicity of the method this test can furnish a wide range of information specially to help in the diagnosis of diseases from the kidneys and the urinary tract. The proper knowledge on the recognition of urinary particles and in the comprehension of the urine sediment profiles are mandatory to develop a work in urinalysis on the highest level possible. This webinar will focus on the different analytical phases of the test specially explaining about the urinary findings observed in the different profiles of diseases that can be identified in urine samples.

Updates on COVID-19 biology and diagnostics

Speaker: Giuseppe LIPPI (IT)
Moderator: Daniel Rajdl (CZ)
Date: 28th May 2020

ABSTRACT : The novel coronavirus disease 2019 (COVID-19) is a pandemic infectious disease sustained by a member of the Coronaviridae family, finally called acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The human-to-human transmission is principally conveyed by droplets or physical contact with infected biological material. The range of clinical pictures is quite heterogeneous, with the vast majority of patients being asymptomatic or only experiencing mild respiratory symptoms. Nevertheless, in nearly 15% and 5% of all patients COVID-19 may progress towards severe or even critical illness, requiring sub-intensive or intensive care. The current death rate is comprised between 6-7%, but is highly variable worldwide depending on genetic, epigenetic and environmental factors. The etiological diagnosis of COVID-19 is, and will remain for long based on direct identification of viral RNA using molecular biology techniques in respiratory tracts samples (especially naso- and oro-pharyngeal swabs). Serological testing has also been recently developed, thus allowing to recognize that most COVID-19 patients develop an immune response against the virus, especially characterized by appearance of IgG and IgA anti-SARS-CoV-2 immunoglobulins one to two weeks after symptoms onset. The availability of rapid tests for detecting either viral antigens or anti-SARS-CoV-2 antibodies has also recently emerged as a valid opportunity for epidemiologic surveillance, though a number of clear quality criteria will need to be fulfilled before any commercially available assay could be safely introduced into clinical practice.

Communication Between Laboratory and Clinician: Key for Proper Medical Care

Date: 19th May 2020 at 18:00 CET

Speaker: Avi Peretz (IL)   Moderator: Dganit Itzhaky (IL)     Webinar manager: Petros Karkalousos (GR)

Laboratory tests results have a decisive influence on the choice of treatment, its success and the prognosis of the patient. In order to ensure the reliability of laboratory test results, a close communication is required between the laboratory and the medical staff. The communication should be expressed in discussion concerning specific cases and the current provision of demographic, clinical and epidemiological information about patients. As the industry moves towards switching to automated systems that perform many laboratory tests in a short time, and with the merger of laboratories, the contact with the medical staff is gradually reduced. As part of the lecture, we will use clinical case studies to provide examples for the importance of the communication between the clinician and the laboratory. The examples will include cases from different laboratories.

Teacher: Avi Peretz

EFLMLabX – exchanging practice in Laboratory Medicine: WHY, HOW to use it?

Date: March 10, 2020 at 18:00 CET
Presenter: Evgenija Homšak (SL), Chair EFLM Profession Committee
Moderator: Sverre Sandberg (NO), past past EFLM president, Member EFLM TFG: Practical Approach to Measurement Uncertainty

Webinar will present the main aims of the project and practical approach how to use the EFLMLabX platform/website https://eflmlabx.eflm.eu/en for application and management for the users and offerers of the practice in Laboratory Medicine.

Essential Leadership Management for Laboratory Professionals

Date: 17th December 2019 at 18:00 CET

Speaker: Sedef Yenice (TR)   Moderator: Diler Aslan (TR)     Webinar manager: Petros Karkalousos (GR)

This webinar introduces a framework for the essential skills of laboratory leadership and concentrates on developing the knowledge and abilities to run a laboratory efficiently and effectively by focusing on self-awareness, understanding effective communication, engaging others, being resourceful, developing empathy and emotional Intelligence.

EFLM Academy: presentation and benefits

Date: 14th November 2019 at 18:00 CET   
Speaker: Ana-Maria Simundic (HR)    Moderator: Sverre Sandberg (NO)   Webinar manager: Daniel Rajdl (CZ) 

The aims of EFLM Academy are:
  • to provide a web domain comprising an information and communication platform; 
  • to support education, training and continuous professional development of laboratory medicine practitioners; and 
  • to raise the profile of EFLM. 

EFLM Academy will be officially launched on January 1st  2020.

Harmonisation of Autoimmune tests

Date: 24th September 2019 at 18:00 CET
Speaker: Joanna Sheldon (UK)    Moderator: Tommaso Trenti (IT)
The importance of standardisation is only just being realised and addressed in autoantibody measurements. Considering all complexities, it is unsurprising that there is marked variation in autoantibody concentrations measured with different methods.  The introduction of certified reference material (CRM) will be the essential first step in standardisation of autoantibody testing and although it does not solve every issue, it should give us a point of reference to identify the other components of the methods that need to be harmonised before we can have comparability in autoantibody results.

How should a medical laboratory specialist prepare for accreditation according to the ISO 15189

Date: 8th October 2019 at 18:00 CET    
Speaker: Diler Aslan (TR)    Moderator: Sedef Yenice (TR)    Webinar manager: Ada Aita (IT)
In this webinar, we will try to explain:
  • how to establish the total testing process and its sub-processes of a medical laboratory (also for a specific analyte that has inherent characteristics) according to the process approach and risk-based quality control;
  • how to correlate the process components to the requirements for the ISO 15189; and
  • which knowledge and competencies are necessary according to the requirements of the ISO 15189.

Monitoring of Internal Quality Control System Using Patients’ Data

Date: 18th June 2019 at 18:00 CET
Speaker: Abdurrahman Coşkun     Moderator: Merve Sibel Gungoren 

We need a real-time monitoring system to detect the possible errors while the instruments are running. The aim of this webinar is to raise awareness for the necessity to monitor analytical instruments continuously while reporting test results. We should monitor the system continuously using a suitable algorithm based on patients’ data.

Unmet clinical needs assessment for biomarker evaluation - a practical toolbox for Laboratory Medicine

Date: 23rd April 2019 at 18:00 CET
Speaker: Phillip Monaghan (UK)   Moderator: Christa Cobbaert (NL)

The EFLM Working Group for Test Evaluation (WG-TE) has developed a ‘practical toolbox’ providing a Test Evaluation Framework and Interactive Unmet Clinical Needs Checklist (hosted on the EFLM eLearning platform) to assist laboratories and other key stakeholders in clinical translational research, to undertake clinical needs assessment and clinical care pathway development.

New parameters of hematology analyzers and their clinical significance

Date: 12th Fbruary 2019 at 18:00 CET
Speaker: Johannes (Hans) Hoffmann (DE)    Moderator: Giuseppe Lippi (IT)

The primary aim of this presentation is to discuss the technological principles used by the major hematology analyzers and to demonstrate how these technologies generate new cellular parameters. The second part will focus on understanding the potential use and limitations of new parameters, which are essential for researchers who are interested in investigating their clinical application.

Sepsis Biomarkers

Date: 22nd January 2019 at 18:00 CET       

Speaker: Giuseppe Lippi      Moderator: Dirk Roggenbuck

Sepsis is a severe, often life-threatening, condition developing when the organism’s response to an infection triggers a paramount biological effect, which finally generate injuries to its own tissues and organs, up to septic shock, multi-organ failure (MOF) and death. Evidence has been provided that the measurement of some biomarkers in serum or plasma may have clinical values for diagnosing and monitoring sepsis.

Pre-analytical mysteries

Date: 27th November 2018 at 18:00 CET     
Speaker: Pieter Vermeersch (BE)    Moderator: Janne Cadamuro (AT)

The order of draw

Date: 15th May 2018 at 18:00CET 
Speaker: Michael Cornes (UK)   Moderator
: João Tiago Guimarães (PT)

How to perform tube validation?

Date: 3rd April 2018 at 18:00 CET   
Speaker: Tiago Guimaraes    Moderator: Giuseppe Lippi

M-protein diagnostics of Multiple Myeloma patients treated with biologics

Date:  27th March 2018 at 14:00 CET   
Speaker: J.F.M. (Hans) Jacobs (NL)   Moderator: Christopher McCudden 

Reliable estimates of biological variation

Date: 06-03-2018 at h. 18.00 CET   
Speaker: Aasne Karine Aarsand (NO)     Moderator: Bill Bartlett (UK)

Laboratory hemostasis

Date: 19th December 2017 at h. 18.00 CET    
Speaker: Giuseppe Lippi (IT)

Harmonization of preanalytical phase in Europe

Date: 21st November 2017 at 18:00 CET   
Speaker: Ana-Maria Simundic (HR)    Moderator: João Tiago Guimarães (PT)

Biomarkers in HF: How to Guide Clinicians

Speaker: Alan S. Maisel (US)     Moderators: Evgenija Homsak (SL) - Kari Pulkki (FI)

Hepatic fibrosis assessment using multiparametric biomarker tests

Date: 18th October 2017 at 18:00 CET  
Speaker: Ralf Lichtinghagen (GER)    Moderator:  Merve Sibel Gungoren (TR)

The estimate of measurement uncertainty

Date: 10th May 2016 at 18 CET    
Speaker: Ilenia Infusino    Moderator:   Anja Kessler

Rational use of laboratory tests

Date: 26th April 2016 at 18:CET
Speaker: Gustav Kováč    Moderator: Mike Hallworth

Management of the quality in the pre-analytical phase

Date: 10th November 2015     

Speaker: Kjell Grankvist     Moderator: Ana-Maria Simundic

Performance specifications in laboratory medicine (Athens 2017)

The course will provide an overview of different models to set performance specifications in laboratory medicine; 1) based on clinical outcome, on 2) biological variation, and 3) state of the art. In addition, it will address the total error concept, and performance specifications in external quality assessment schemes and in the extra-analytical phases.

Cardiac Markers (Athens 2017)

The availability of highly sensitive troponin assays (hsTn) allows the safe clinical application of international recommendations and the introduction of fast-track protocols for the definition of AMI. However, hsTn assays have not always been welcomed by clinicians, claiming an increase in false-positive results. To guide interpretation of results, laboratory specialists need to get involved in communicating with clinicians through education, test interpretation and internal audits of test usage and patient outcomes.

Promoting clinical and laboratory interaction by harmonization

A recording of a plenary presentation by professor Mauro Panteghini, recorded at 4th Joint EFLM-UEMS Congress: Warsaw, Poland, 21–24 September, 2016

Cystatin C as a marker of GFR in children

Presenter: Arend Bökenkamp (Department of Pediatric Nephrology, VU University Medical Center, Amsterdam, Netherlands)

The presentation reviews the characteristics of cystatin C from a clinical point of view, focusing on its use in children.

The role of pharmacogenetics in therapeutic drug monitoring of immunosuppressive drugs

presented by: prof. Dennis Hesselink, Erasmus MC, University Medical Center Rotterdam, Department of Internal Medicine, Division of Nephrology and Kidney Transplantation,
Rotterdam, the Netherlands

recorded at the 4th Joint EFLM-UEMS Congress “Laboratory Medicine at the Clinical Interface”, Warsaw, Poland, 21th–24th September, 2016

Teacher: Daniel Rajdl

Task Force “European Regulatory Affairs”

Discussion and information forum

Restricted access to TF-ERA members and National Societies Representatives.

Unmet clinical needs

The unmet clinical need checklist produced by the EFLM Test Evaluation Working Group (TE-WG) is a practical tool to assist the work of professionals involved in the discovery or implementation of new biomarkers. The tool is aligned with the IOM recommendations and the FDA and CE regulating body’s requirements. An interactive version of the checklist is available in this course. We encourage pilot testing and regular use of the checklist and the TE-WG would appreciate feedback which would inform future refinements of the checklist based on users’ experience.